The synthesis of a new benzothiazine derivative, related to oxicams, synthesized from natural safrole [1]FRAGA, C. A. M; BARREIRO, E. J.Journal of heterocyclic chemistry. 1992, Vol 29, Num 6, pp 1667-1669, issn 0022-152XArticle

Synthesis of pyrazole derivatives as potential bioisosteres of thromboxane-synthetase inhibitorsBARREIRO, E. J; FREITAS, A. C. C.Journal of heterocyclic chemistry. 1992, Vol 29, Num 2, pp 407-411, issn 0022-152XArticle

LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligationTRIBUTINO, J. L. M; SANTOS, M. L. H; MIRANDA, A. L. P et al.British journal of pharmacology. 2010, Vol 159, Num 8, pp 1716-1723, issn 0007-1188, 8 p.Article

Cyclic GMP-dependent vasodilatory properties of LASSBio 294 in rat aortaSILVA, C. L. M; NOËL, F; BARREIRO, E. J et al.British journal of pharmacology. 2002, Vol 135, Num 1, pp 293-298, issn 0007-1188Article

Studies on antiplatelet agents from natural safrole. II. Synthesis and pharmacological properties of novel functionalized oxime O-benzylether derivativesREIS, A. L. De A; ORMELLI, C. B; MIRANDA, A. L. P et al.Pharmaceutica Acta Helvetiae. 1999, Vol 74, Num 1, pp 19-28, issn 0031-6865Article

Synthesis and evaluation of analgesic, antiinflammatory and antiplatelet properties of new 2-pyridylarylhydrazone derivativesTODESCHINI, A. R; DE MIRANDA, A. L. P; DA SILVA, K. C. M et al.European journal of medicinal chemistry. 1998, Vol 33, Num 3, pp 189-199, issn 0223-5234Article

Synthesis and pharmacological evaluation of a new class of bicyclic phospholipids, designed as platelet activating factor antagonistsPOLEY PECANHA, E; MANSSOUR FRAGA, C. A; RABELLO DE SANTANNA, C. M et al.Il Farmaco (Pavia). 1998, Vol 53, Num 5, pp 327-336, issn 0014-827XArticle

Toxicological in vitro and subchronic evaluation of LASSBio-596ARAUJO, G. L; VIEIRA, A. E. D; COSTA, M. L et al.Food and chemical toxicology. 2014, Vol 73, pp 148-156, issn 0278-6915, 9 p.Article

Development and validation of a LC-MS/MS method with electrospray ionization for determination of LASSBio-579 in rat plasmaCONRADO, D. J; PALMA, E. C; FRAGA, C. A. M et al.Journal of pharmaceutical and biomedical analysis. 2007, Vol 43, Num 2, pp 677-682, issn 0731-7085, 6 p.Article

Selective PGHS-2 inhibitors: A rational approach for treatment of the inflammationRODRIGUES, C. R; VELOSO, M. P; VERLI, H et al.Current medicinal chemistry. 2002, Vol 9, Num 8, pp 849-867, issn 0929-8673Article

The new compound, LASSBio 294, increases the contractility of intact and saponin-skinned cardiac muscle from Wistar ratsSUDO, R. T; ZAPATA-SUDO, G; BARREIRO, E. J et al.British journal of pharmacology. 2001, Vol 134, Num 3, pp 603-613, issn 0007-1188Article

Expeditions, stereocontrolled sytnheses of racemic and natural brasilenol through intramolecular asymmetry transfer Absolute stereochemistry of brasilenolGREENE, A. E; SERRA, A. A; BARREIRO, E. J et al.Journal of organic chemistry. 1987, Vol 52, Num 6, pp 1169-1170, issn 0022-3263Article

Anti-inflammatory profile of N-phenylpyrazole arylhydrazone derivatives in ratsBARJA-FIDALGO, C; FIERRO, I. M; BRANDO LIMA, A. C et al.Journal of pharmacy and pharmacology. 1999, Vol 51, Num 6, pp 703-707, issn 0022-3573Article

Proposal of a new PAF pharmacophoric map by the AM1 methodRODRIGUES, C. R; BICCA DE ALENCASTRO, R; BARREIRO, E. J et al.European journal of pharmaceutical sciences. 1999, Vol 8, Num 4, pp 309-315, issn 0928-0987Article

Synthesis and antinociceptive properties of new structurally planned imidazo[1,2-a]pyridine 3-acylarylhydrazone derivativesRIBEIRO, I. G; DA SILVA, K. C. M; PARRINI, S. C et al.European journal of medicinal chemistry. 1998, Vol 33, Num 3, pp 225-235, issn 0223-5234Article

Antinociceptive property of new 4-acyl-arylhydrazone pyrazole compoundsMATHEUS, M. E; OLIVEIRA, L. F; FREITAS, A. C. C et al.Brazilian journal of medical and biological research. 1991, Vol 24, Num 12, pp 1219-1222, issn 0100-879XArticle

Substituted pyrazolylhydrazones : a new class of platelet aggregation inhibitorsSILVEIRA, I. A. F. B; PAULO, L. G; MIRANDA, A. L. P et al.Brazilian journal of medical and biological research. 1991, Vol 24, Num 9, pp 947-951, issn 0100-879XArticle

Synthesis and analgesic activity of novel N-acylarylhydrazones and isosters, derived from natural safroleLIMA, P. C; LIMA, L. M; DA SILVA, K. C. M et al.European journal of medicinal chemistry. 2000, Vol 35, Num 2, pp 187-203, issn 0223-5234Article

Synthesis and antiplatelet evaluation of novel aryl-sulfonamide derivatives, from natural safroleLIMA, L. M; ORMELLI, C. B; BRITO, F. F et al.Pharmaceutica Acta Helvetiae. 1999, Vol 73, Num 6, pp 281-292, issn 0031-6865Article

Synthesis and analgesic profile of novel N-containing heterocycle derivatives : arylidene 3-phenyl-1,2,4-oxadiazole-5-carbohydrazideLEITE, L. F. C. C; RAMOS, M. N; BOSCO P. DA SILVA, J et al.Il Farmaco (Pavia). 1999, Vol 54, Num 11-12, pp 747-757, issn 0014-827XArticle

Diastereomeric analysis of bioactive N-phenylpyrazole-4-acylhydrazone derivatives by high resolution gas chromatographyPEREIRA, A. S; VIOLANTE, F. A; AQUINO, F. R et al.Analytical letters. 1998, Vol 31, Num 4, pp 719-732, issn 0003-2719Article

Design and synthesis of a new 4-oxa-8ω-11-deoxy-5,6-dihydroprostacyclin analogueFRAGA, C. A. M; MIRANDA, A. L. P; BARREIRO, E. J et al.Chemical and pharmaceutical bulletin. 1996, Vol 44, Num 11, pp 2157-2161, issn 0009-2363Article

Structures of pyrazole derivatives. III: 5-amino-4-cyano-1-phenylpyrazoleZUKERMAN-SCHPECTOR, J; BARREIRO, E. J; FREITAS, A. C. C et al.Acta crystallographica. Section C, Crystal structure communications. 1994, Vol 50, pp 2095-2096, issn 0108-2701, 12Article

New pyrazolylhydrazone derivatives as inhibitors of platelet aggregationFREITAS BRASILEIRO DA SILVEIRA, I. A; GONCALVES PAULO, L; PALHARES DE MIRANDA, A. L et al.Journal of pharmacy and pharmacology. 1993, Vol 45, Num 7, pp 646-649, issn 0022-3573Article

Structures of pyrazole derivatives. I: A potential bioisoster of thromboxane synthetase inhibitorsCARACELLI, I; ZUKERMAN-SCHPECTOR, J; BARREIRO, E. J et al.Acta crystallographica. Section C, Crystal structure communications. 1993, Vol 49, pp 633-635, issn 0108-2701, 3Article